Mitchell P Levesque Selected Research

SOXE Transcription Factors

1/2020	Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
1/2015	Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.

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Mitchell P Levesque Research Topics

Disease

72	Melanoma (Melanoma, Malignant) 06/2022 - 04/2012
47	Neoplasms (Cancer) 06/2022 - 04/2012
10	Neoplasm Metastasis (Metastasis) 06/2022 - 01/2016
5	Inflammation (Inflammations) 12/2022 - 02/2015
4	Brain Neoplasms (Brain Tumor) 10/2021 - 01/2017
4	Carcinogenesis 01/2021 - 11/2018
2	Tertiary Lymphoid Structures 01/2022 - 01/2018
2	Bites and Stings (Sting) 01/2022 - 01/2021
2	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2021 - 02/2015
2	Residual Neoplasm 01/2021 - 03/2015
2	Testicular Neoplasms (Testicular Cancer) 10/2020 - 01/2019
2	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 04/2016 - 04/2014
1	Basal Cell Carcinoma (Rodent Ulcer) 04/2022
1	Disease Progression 01/2022
1	Necrosis 12/2021
1	Lymphatic Metastasis 12/2021
1	Ewing Sarcoma (Sarcoma, Ewing) 07/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2020
1	Laminopathies 10/2020
1	Colitis 08/2020
1	Wounds and Injuries (Trauma) 01/2020
1	Fibrosis (Cirrhosis) 01/2020

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 06/2022 - 01/2015
12	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2018
8	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 01/2017
7	Biomarkers (Surrogate Marker)IBA 06/2022 - 01/2018
7	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2015
6	Pharmaceutical PreparationsIBA 04/2022 - 04/2012
6	Phosphotransferases (Kinase)IBA 01/2022 - 04/2012
4	ChemokinesIBA 01/2022 - 03/2015
4	CytokinesIBA 01/2022 - 03/2015
4	Adapalene (Differin)FDA LinkGeneric 12/2021 - 01/2014
4	Mitogen-Activated Protein KinasesIBA 01/2021 - 03/2016
4	CateninsIBA 01/2020 - 01/2018
3	InterferonsIBA 01/2022 - 01/2013
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2019
3	Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA 12/2021 - 12/2017
2	Adenosine Monophosphate (AMP)IBA 01/2022 - 12/2020
2	Peptides (Polypeptides)IBA 12/2021 - 01/2021
2	Interleukin-12 (IL 12)IBA 10/2021 - 02/2015
2	Biological ProductsIBA 01/2021 - 05/2019
2	NivolumabIBA 12/2020 - 11/2017
2	Programmed Cell Death 1 ReceptorIBA 12/2020 - 01/2018
2	AntibodiesIBA 12/2020 - 01/2019
2	Glutathione (Reduced Glutathione)IBA 11/2020 - 11/2015
2	AntigensIBA 10/2020 - 01/2019
2	A-factor (Streptomyces)IBA 01/2020 - 01/2015
2	SOXE Transcription FactorsIBA 01/2020 - 01/2015
2	Immunoglobulin G (IgG)IBA 01/2019 - 01/2019
1	CD146 AntigenIBA 12/2022
1	MicroRNAs (MicroRNA)IBA 06/2022
1	Lipid Bilayers (Lipid Bilayer)IBA 06/2022
1	Protein Kinases (Protein Kinase)IBA 01/2022
1	Toll-Like Receptor AgonistsIBA 01/2022
1	TL8-506IBA 01/2022
1	Toll-Like Receptor 8IBA 01/2022
1	YY1 Transcription FactorIBA 01/2022
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2022
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 01/2022
1	Complement C3 (C3 Complement)IBA 01/2022
1	Peptide Hydrolases (Proteases)FDA Link 01/2022
1	Interleukin-33IBA 01/2022
1	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 12/2021
1	Amyloid (Amyloid Fibrils)IBA 12/2021
1	Interleukin-23 Subunit p19IBA 10/2021
1	Imiquimod (Aldara)FDA LinkGeneric 10/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2021
1	PolyphenolsIBA 07/2021
1	EnzymesIBA 01/2021
1	Stem Cell FactorIBA 01/2021
1	AnisomycinIBA 01/2021
1	16S Ribosomal RNAIBA 01/2021
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2021
1	Androgen Receptors (Androgen Receptor)IBA 01/2021
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2021
1	MidkineIBA 12/2020
1	Adenosine (Adenocard)FDA LinkGeneric 12/2020
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2020
1	pembrolizumabIBA 12/2020
1	CTLA-4 AntigenIBA 12/2020
1	Mitogen-Activated Protein Kinase 3IBA 11/2020
1	mirdametinibIBA 11/2020
1	Immunoglobulins (Immunoglobulin)IBA 10/2020
1	Lamin Type A (Lamin A)IBA 10/2020
1	SteroidsIBA 08/2020
1	Zinc Finger E-box Binding Homeobox 2IBA 01/2020
1	Tyrosine Kinase InhibitorsIBA 01/2020
1	F-Box ProteinsIBA 01/2020
1	takinibIBA 01/2020
1	Protein Isoforms (Isoforms)IBA 01/2020
1	trametinibIBA 01/2020
1	glycogen synthase kinase 3 alphaIBA 01/2020
1	Biocompatible Materials (Biomaterials)IBA 01/2020
1	Deoxyglucose (2 Deoxy D glucose)IBA 01/2020
1	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA 11/2019

Therapy/Procedure

40	Therapeutics 06/2022 - 01/2013
13	Immunotherapy 01/2022 - 02/2013
4	Drug Therapy (Chemotherapy) 12/2021 - 01/2017
2	Radiotherapy 05/2021 - 12/2020
2	Precision Medicine 10/2019 - 01/2017